Welcome To Bhagwat Lab


The research in our group is focused on elucidating cellular processes such as DNA damage caused by endogenous reactive chemical species,

DNA methylation, transcription, replication, and cytosine deamination due to human AID/APOBEC enzymes that promote mutations.

We also study the interplay between these processes and DNA repair in the prevention or promotion of human cancers.

 

Our multidisciplinary approach to understanding mutagenesis includes use of analytical techniques such as

mass-spectrometry, chemical synthesis, protein and nucleic acid biochemistry, genetics and cutting-edge

cellular and molecular biology methods including genomics and bioinformatics.